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・ Toxic equivalency factor
・ Toxic food environment
・ Toxic Girl
・ Toxic granulation
・ Toxic Grind
・ Toxic heavy metal
・ Toxic Holocaust
・ Toxic Holocaust / Inepsy
・ Toxic Holocaust / Midnight
・ Toxic Holocaust / Oprichniki
・ Toxic hotspot
・ Toxic injury
・ Toxic Kids
・ Toxic leader
・ Toxic Legacy
Toxic leukoencephalopathy
・ Toxic Love
・ Toxic megacolon
・ Toxic multinodular goitre
・ Toxic Narcotic
・ Toxic nodular goiter
・ Toxic oil syndrome
・ Toxic Reasons
・ Toxic Shock Records
・ Toxic shock syndrome
・ Toxic shock syndrome toxin
・ Toxic sludge spill
・ Toxic Small RNA
・ Toxic Substances Control Act of 1976
・ Toxic Thrash Metal


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Toxic leukoencephalopathy : ウィキペディア英語版
Toxic leukoencephalopathy
Toxic leukoencephalopathy or toxic spongiform leukoencephalopathy is a rare condition that is characterized by progressive damage (-pathy) to white matter (-leuko-) in the brain (-encephalo-), particularly myelin, due to causes such as exposure to drugs of abuse, environmental toxins, or chemotherapeutic drugs. The prevalence of this disease is infrequent and often goes unreported, especially in cases resulting from drug abuse. Magnetic resonance imaging (MRI) is a popular method to study and diagnose the disease. However, even with technological advances, the exact mechanism and underlying pathophysiology of toxic leukoencephalopathy remains unknown and is thought to vary between sources of toxicity. The clinical severity of toxic leukoencephalopathy also varies among patients, exposure time, and concentration and purity of the toxic agent. Some reversibility of the condition has been seen in many cases when the toxic agent is removed.
== Causes ==
Various pharmacological agents have been known to cause toxic leukoencephalopathy. The most common causes are substance abuse drugs and chemotherapy; however, the disease has also occurred on the rare occasion as a side effect to certain medications and environmental toxins.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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